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- W2378412327 abstract "The methods for the treatment of advanced renal cell carcinoma are not ideal,especially metastatic renal cell carcinoma. The efficacy of drug for the treatment of advanced renal cell carcinoma is limited. We need a new molecular marker for clinical application. It can be easily used to the risk assessment of renal cell carcinoma,and select more positive treatment methods for the patients,and become the new target of molecular biological treatment. MicroRNA( MiRNA) is a small non-coding RNA molecule,and involve in many processes of cellular physiology and pathology. MiRNA has a post-transcriptional regulation function,and can regulate the translation of messenger RNA( mRNA). In many studies,miRNA was found to be involved in many biological processes associated with renal cell carcinoma. By changing its expression level,it can regulate tumor cell occurrence,proliferation and apoptosis. Therefore,through the study on the regulation of miRNA in renal cell carcinoma,we may find new ways as a marker for early diagnosis of renal cell carcinoma,and as a new biological marker for prognostic risk assessment and treatment therapeutic target." @default.
- W2378412327 created "2016-06-24" @default.
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- W2378412327 date "2014-01-01" @default.
- W2378412327 modified "2023-09-25" @default.
- W2378412327 title "Regulation Mechanism and Application of MicroRNAs in Renal Cell Carcinoma" @default.
- W2378412327 hasPublicationYear "2014" @default.
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