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- W2378412500 abstract "Essential genes are indispensable for the survival of an organism in optimal conditions. Recently, study on essential gene is becoming a hot topic of microbiology, genomics, and bioinformatics. This paper described the experiments that determined essential genes in some microbes and the theoretical researches on essential genes were reviewed. The major content contained comparison of essential genes and non-essential genes based on information on evolutionary conservation and sequence composition, and in silico prediction of essential genes, and analysis of the chromosomal distributions of essential genes. Finally, related progresses were concluded and the open problems were pointed out." @default.
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- W2378412500 date "2012-06-26" @default.
- W2378412500 modified "2023-09-23" @default.
- W2378412500 title "Current status of theoretical studies on essential genes in microbes" @default.
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- W2378412500 doi "https://doi.org/10.3724/sp.j.1005.2012.00420" @default.
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