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- W2378437613 abstract "To investigate the clinical curative effects of nifedipine combined with salvia miltiorrhiza for patients with mild and moderate pregnancy-induced hypertension syndrome(PIH) and the impact on coagulation function and hemorrheologic indexes. Eighty patients were randomly divided into observation group and control group,40 patients each.All the patients were treated with conventional therapy.The control group was supplemented with nifedipine,while the observation group supplemented with nifedipine and salvia miltiorrhiza injection.The course of treatment was 14 days.The clinical curative effects and the changes in coagulation-function and hemorheology between the two groups were compared. The total effective rate of patients in the observation group was 90%,significantly higher than that of the control group(70%)(P 0.05).After treatments,in all patients the plasma prothrombin time(PT) and activated partial thromboplastin time(APTT) were significantly higher,while fibrin(Fbg) levels were significantly lower after the treatment than those before treatments(P 0.05).However,the improvement of these parameters in the observation group was significantly better than that of the control group(P 0.01).Moreover,in all patients the whole blood viscosity,plasma viscosity,and hematocrit were significantly decreased after treatment compared to treatment before(P 0.05).Again,the observation group were decreased more significantly(P 0.01). The combination of salvia miltiorrhiza with nifedipine in the treatment of mild and moderate PIH has good clinical therapeutic effects to improve coagulation-functional and hemorrheologic abnormalities.Therefore,it is highly safe and worthy of clinical application." @default.
- W2378437613 created "2016-06-24" @default.
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- W2378437613 date "2013-01-01" @default.
- W2378437613 modified "2023-09-23" @default.
- W2378437613 title "The curative effect of nifedipine combined with salvia miltiorrhiza for patients with mild and moderate gestation hypertension syndrome and impact on the coagulation-function and hemorheology" @default.
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