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- W2378468267 abstract "Objective To study the localization of efferent neuron and its terminals of artificial somatic-autonomic reflex arc.Methods The artificial somatic-autonomic reflex pathway was established in rat by intra-dural microanastomosis of the left L4 ventral root to L6 ventral root.The 11 model rats were divided into three groups (n=4,4,3 respectively).Retrograde tracing technique with fluorogold (FG),fast blue (FB) and horseradish peroxidase (HRP) and antegrade tracing with malt agglutinator binding horseradish Peroxidase (WGA-HRP) were applied.Results After FG was injected into the left major pelvic ganglia (MPG) and FB was injected into the external urethral sphincter (EUS),FG or FB single labeled neurons and FG-Fbdual labeled neurons were observed in locus of the left ventral horn from L3 caudal to L5 rostral.HRP positive neurons were observed in the left MPG but not in spinal cord after HRP was injected into the bladder detrusor.After WGA-HRP was injected into L4 left ventral horn,HRP positive axon terminals were observed in the left MPG and EUS,not in the detrusor.Conclusion Somatic motor axons(L4VR)can regenerate into peripheral autonomic and somatic motor nerve fibers.Some of regenerate nerve fibers directly terminated EUS,and others terminated the MPG.Postganglionic neurons that project to the bladder were distributed in the MPG;Simultaneous reinnervation of MPG and EUS by one group of somatic motor neurons may be the major neural anatomy infrastructure for controllable voiding via the somatic-autonomic reflex arc." @default.
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- W2378468267 date "2003-01-01" @default.
- W2378468267 modified "2023-09-24" @default.
- W2378468267 title "Neural tracing study of efferent pathway of the artificial somatic-autonomic reflex arc" @default.
- W2378468267 hasPublicationYear "2003" @default.
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