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- W2378496656 abstract "Objective To investigate the relationship between paraoxonase activities(PON) and Malondialdehyde(MDA)and lipid profile in pre-eclampsia and the severity of pre-eclampsia. Methods 60 PE pregnant women were involved in the study as experiment group,and 40 healthy pregnant women in advanced stage were involved as control study.The changes of the levels of PON activity,MDA and lipid profile in the serum of the patients with pre-eclampsia were detected. Results Compared with that of patients with mild pre-eclampsia group((115.80±27.25)kU/L),the serum PON activity of patients with severe pre-eclampsia group((81.86±29.68) kU/L) was significantly lower(P0.01).The serum PON activity in the mild pre-eclampsia group was significantly lower than that of the patients in the control group(P0.05).Compared with those of mild preeclampsia group((5.16±1.02)nmol/L),the serum MDA of severe preeclampsia group((7.11±1.52)nmol/L) were significantly higher(P0.01).The serum MDA levels in the mild preeclampsia group were also significantly higher than those in the control group(P0.05).The serum TG and LDL-C levels in the experiment group were significantly higher than those in the control group(P0.05).The serum HDL-C level in the experiment group was significantly lower than that in the control group(P0.05). Conclusion The PON activity,MDA and lipid profile of the patients with pre-eclampsia is related to the pathogenesis as well as the severity of preeclampsia." @default.
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- W2378496656 date "2011-01-01" @default.
- W2378496656 modified "2023-09-23" @default.
- W2378496656 title "Relations between Paraoxonase Activities and Malondialdehyde with Lipid Profile in Pre-eclampsia" @default.
- W2378496656 hasPublicationYear "2011" @default.
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