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- W2378499200 abstract "AIM:To evaluate the effects of the angiotensin-converting enzyme(ACE) inhibitor imidapril and benazepril on the peripheral blood pressure and the central blood pressure in patients with essential hypertension. METHODS:A double blind,randomized study was carried out after 2 wk placebo run-in period,patients with mild or moderate essential hypertension,aged 18-79 a old,were randomized to receive either imidapril(5-10 mg,po,qd) or benazepril(10-(20 mg),po,qd) for 6 wk of treatment.Before the active treatment and at the end of the study,pulse wave recordings were performed in all the patients. Only those patients have finished 6 wk of active treatment in both groups were included to have the final analysis. RESULTS:Ninety-eight patients had finished the whole study with complete data,showing no significant difference(all P(0.05)) basically between the two groups. After 6 wk of treatment,there were significant reduction in all observed parameters of pulse wave(all P(0.05)),but no significant differences(all P(0.05)) in the reduced values of all observed parameters of pulse wave between two groups except brachial pulse pressure and increase augmentation index. CONCLUSION:Imidapril and benazepril are both similarly effective in the reduction of the peripheral blood pressure and the central blood pressure in the treatment of hypertension." @default.
- W2378499200 created "2016-06-24" @default.
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- W2378499200 date "2005-01-01" @default.
- W2378499200 modified "2023-09-27" @default.
- W2378499200 title "Comparison of imidapril and benazepril on central and peripheral blood pressures through pulse wave analysis" @default.
- W2378499200 hasPublicationYear "2005" @default.
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