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- W2378508725 abstract "Objective To investigate the expression of serum hepcidin in chronic renal failure(CRF) patients after using erythropoietin(EPO).Methods Totally 30 CFR patients were enrolled in this study.Serum Fe,ferritin(FER),total iron binding capacity(TIBC),transferrin(TRF) and hemoglobin were measured by routine methods.The levels of serum hepcidin and interleukin 6 were measured by enzyme-linked immunosorbent assay(ELISA).Data were compared between the two groups.Results After the application of EPO,the level of serum hepcidin decreased from(208.67 ± 40.34) μg / L to(154.28 ± 31.37) μg / L(P 0.05);the level of hemoglobin increased from(82.31 ± 12.41) g / L to(99.43 ± 11.82) g / L(P 0.05).After the treatment,the levels of Serum Fe,TRF and TIBC increased while the levels of FER decreased(P 0.05).The levels of SCr did not changed obviously.The levels of hs-CRP decreased from(4.53 ± 2.11) mg / L to(2.84 ± 0.92) mg / L(P 0.05);But the level of IL-6 did not changed significantly(P 0.05).Conclusion The level of serum hepcidinl can be regulated by EPO in CRF patients and anaemia can be improved." @default.
- W2378508725 created "2016-06-24" @default.
- W2378508725 creator A5061337643 @default.
- W2378508725 date "2013-01-01" @default.
- W2378508725 modified "2023-09-23" @default.
- W2378508725 title "Expression of Serum Hepcidin in Chronic Renal Failure Patients after Using Erythropoietin" @default.
- W2378508725 hasPublicationYear "2013" @default.
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