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- W2378515868 abstract "[Objective] To study the protective effect of Hemerocallis fulva on acute liver injury.[Method] 60 mice were randomly divided into 6 groups defined as blank control group,positive drug group,high,medium,low H.fulva prevention group;micro-ELISA method was used for the determination of alanine aminotransferase,aspartate aminotransferase;right lobe of the liver homogenate after detection kit was adopted to detect SOD activity and MDA content;one-way ANOVA was adopted for statistical processing.[Result] Compared with normal group,serum GOT,GPT,liver MDA content in model group was significantly higher,liver SOD activity was lower than in the control group;compared with the model group,Chinese herbal medicines and high-dose,middle-dose H.fulva prevention group,serum GOT,GPT,liver MDA content were significantly lower,liver SOD activity increased,which showed obvious difference with blank control group;Mice liver in model group appeared degradation and necrosis of liver cells while Chinese herbal medicine prevention group and H.fulva prevention group improved at different degree.[Conclusion] The experiment successfully copied a mouse model of acute liver injury,liver tablets and H.fulva extracts have a protective effect on CCl4-induced acute liver injury." @default.
- W2378515868 created "2016-06-24" @default.
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- W2378515868 date "2012-01-01" @default.
- W2378515868 modified "2023-09-28" @default.
- W2378515868 title "Protective Effect of Hemerocallis fulva on Carbon Tetrachloride Induced Acute Liver Injury" @default.
- W2378515868 hasPublicationYear "2012" @default.
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