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- W2378551207 abstract "Objective To observe and analyze NPCs amount and density in each spinal cord cervical segment of adult mice.Methods Experimental investigation of neural precursor cells (NPCs) distributed feature in spinal cord cervical segment of adult animal was conducted by nestin second-intron enhancer controlled LacZ reporter transgenic mice (pNes-Tg).The pNes-Tg transgenic mice,LacZ staining and positive cell quantifications were used.Results NPCs were observed in whole spinal cord cervical segment of adult mice,but amount and density was different in different region.The dorsal horn region was the most and the next was central canal.The ventral and lateral horn was less in spinal cord.In dorsal horn region NPCs mainly distributed in substantia gelatinosa,in central canal NPCs mainly distributed in ependymal zone,the medullae,nucleus regions in spinal cord were less. There were no difference between the left and right sides.Conclusion The results suggested that NPCs distribution possibly are relative to damage and recovery of spinal cord in clinical diseases, the regions where are difficult to recover and easy to damage like ventral and lateral horn were less,oppositely,in dorsal and central canal were more." @default.
- W2378551207 created "2016-06-24" @default.
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- W2378551207 date "2008-01-01" @default.
- W2378551207 modified "2023-09-25" @default.
- W2378551207 title "Distribution Feature of Neural Precursor Cells in Spinal Cord Cervical Segment of Adult Mice" @default.
- W2378551207 hasPublicationYear "2008" @default.
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