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- W2378575437 abstract "Objective To investigate the changes of Th1/Th2 cell ratio in the peripheral blood of patients with both coronary heart disease and diabetes,to speculate that the role what the imbalance of Th1/Th2 cells play in atherosclerosis.Methods To extract the peripheral blood mononuclear cells(PBMC)of 94 cases[32 patients with CHD,36 patients with both coronary heart disease and diabetes mellitus(CHD+DM),26 healthy controls],the Th1/Th2 cell ratio were tested by flow cytometry.Finally,we analyzed the changes of Th1/Th2 cell ratio.Results Compared with control group,the level of Th1 cells of CHD group was significantly higher,and there was significant difference(P0.01);the level of Th2 cells was lower than the control group patients,there was significant difference(P0.05).Compared with the CHD group and control group,the level of Th1 cells of the CHD+DM group was significantly higher(P0.01).The difference in levels of Th2 cells between the control,CHD and CHD+DM groups was also significant(P0.05).Conclusions Compared with patients with normal blood glucose,diabetic patients with coronary heart disease had a more serious Th1/Th2 imbalance and combined more severe immune and inflammatory responses." @default.
- W2378575437 created "2016-06-24" @default.
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- W2378575437 date "2011-01-01" @default.
- W2378575437 modified "2023-09-23" @default.
- W2378575437 title "Changes of Th1/Th2 cell ratio in the peripheral blood of patients with both coronary heart disease and diabetes" @default.
- W2378575437 hasPublicationYear "2011" @default.
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