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- W2378618140 abstract "Objective To investigate the relationship between portal hypertension gastrosia (PHG)and HBV infection using immunohistochemistry technique.Method The143cases of liver cirrhosis with PHG were given endoscope examination and gastric mucosa was taken for pathology examination.HBV antigen in gastric mucosa was detected by immunohistochemistry and HBV antigen and HBV DNA in serum were detected by ELISA and PCR respectively.The pathologic changes were divided into slight ,moderate and severe degrees.The control group were the patients with chronic HBV infection without portal hypertension.Results No marked difference could be found between two groups.The positivity rate of HBsAg and HBcAg in gastric mucosa in the studied group was higher than that in the control group,36.36%and25.87%vs27.61%and16.67%,respectively (P0.01),indicating that there was positive correlation between the degree of PHG pathology and the positivity rate of HBV antigen in gastric mucosa.The HBsAg positivity rate of slight,moderate and severe degrees of PHG was20.96%,29.78%and64.70%respectively and HBcAg positive rate was16.12%,25.53%and44.11%respectively,(P0.01).Conclusion The prevalence of PHG would be related to HBV infection." @default.
- W2378618140 created "2016-06-24" @default.
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- W2378618140 date "2003-01-01" @default.
- W2378618140 modified "2023-09-23" @default.
- W2378618140 title "Immunohistochemistry study on the relationship between portal hypertension gastrosia and HBV infection" @default.
- W2378618140 hasPublicationYear "2003" @default.
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