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- W2378618214 abstract "Objective To study the cytotoxicity of chitosan thermosensitive hydrogel to human gingival fibroblasts(HGF)for its application in the treatment of periodontal diseases.Methods Human gingival fibroblasts were cultured in a medium containing chitosan thermosensitive hydrogel at different concentrations for 24,48,72,and 96h,respectively.The relative growth rate(RGR)of HGF was determined by MTT assay.Results The relative growth rate of HGF was over 90%after cultured for different periods of time.The cytotoxicity grade of different concentrations of chitosan thermosensitive hydrogel was 0 and 1.Conclusion RGR have no cytotoxicity to HGF.Local application of chitosan thermosensitive hydrogel in the treatment of periodontal diseases is feasible." @default.
- W2378618214 created "2016-06-24" @default.
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- W2378618214 date "2009-01-01" @default.
- W2378618214 modified "2023-09-23" @default.
- W2378618214 title "Cytotoxicity of chitosan thermosensitive hydrogel to human gingival fibroblasts in vitro" @default.
- W2378618214 hasPublicationYear "2009" @default.
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