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- W2378619135 abstract "Objective:To determine if focal liver lesions could be differentiated as malignant or benign on the basis of conventional MRI and apparent diffusion coefficient(ADC) alone and in combination.Methods: A total of 49 patients with focal liver lesions proved pathologically were examined with conventional MR sequences and diffusion-weighted imaging.Twenty-eight patients were diagnosed with malignant tumors and were appointed a case group,the rest were a randomly selected to a control group of 22 patients with benign lesions.First,all images of conventional MR sequences were reviewed by two radiologist blinded to the clinical data and group.Sensitivity and specificity of conventional MRI were calculated.Secondly,the ADC values of all lesions were measured by two radiologist.The values of conventional MR sequences,ADC values,and a combination of both in diagnosing malignant tumors were evaluated by receiver operating characteristic(ROC) curve analysis.Results: For focal liver lesions,the mean ADC values of malignant tumors and benign lesions were(1.29 ± 0.53) ×10-3mm2/s,(1.88 ± 0.79) ×10-3mm2/s respectively.Combination of ADC values and conventional MRI resulted in the highest diagnostic accuracy,and the sensitivity,specificity,and accuracy respectively were(92.9%,95.0%,93.9% vs 96.4%,80.0%,and 89.8% for conventional MRI alone and 82.1%,90.0%,and 83.7% for ADC values alone).Conclusions: The combined use of ADC values with conventional MRI helps to provide higher diagnostic accuracy than conventional MRI alone in the detection of focal liver lesions.The measurements of the ADCs of focal liver lesions may represent a useful complementary tool for lesion characterization." @default.
- W2378619135 created "2016-06-24" @default.
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- W2378619135 date "2011-01-01" @default.
- W2378619135 modified "2023-09-23" @default.
- W2378619135 title "The Value of Apparent Diffusion Coefficient Combined with Conventional MRI in Characterization of Focal Liver Lesions" @default.
- W2378619135 hasPublicationYear "2011" @default.
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