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- W2378620635 abstract "Objective:To study effect of the high-power microwave(HPM) exposure on rat BBB.Methods:Sixty sixWistar rats were exposed to high-power microwave at 10,30 and 100 mW/cm2and sacrificed with 2%K4Fe(CN)6and4.2% Fe2(SO4)3at 6 h and on d1,d3 and d7 after the exposure.The capillary structure,the BBB permeability to indica-tor and the changes in GFAP expression were examined by means of HE,immunohistochemistry and image analysis.Results:No changes were found in the rat brains at 10 mW/cm2.It was found that the permeability was increased withedema and wide capillary gap at30 and 100 mW/cm2.These changes peaked on d3 and recovered on d7.The changes af-ter 100 mW/cm2exposure were more severe than those after30 mW/cm2.The GFAP expression was increased in the cortexand hippocampus after 30 and 100 mW/cm2exposure,peaked on d3 and was still higher than that of the sham exposuregroup on d7.Conclusion:High-power microwave at 30 and 100 mW/cm2can damage the BBB structure and function." @default.
- W2378620635 created "2016-06-24" @default.
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- W2378620635 date "2006-01-01" @default.
- W2378620635 modified "2023-09-23" @default.
- W2378620635 title "Effect of high-power microwave exposure on rat blood-brain barrier" @default.
- W2378620635 hasPublicationYear "2006" @default.
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