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- W2378620870 abstract "Ca 2+ influx evoked across the plasma membrane upon internal store depletion is essential for a myriad of cellular functions including gene expression, cell proliferation, differentiation and even apoptosis. Dariers disease (DD), an autosomal dom- inant inherited disorder of the skin, arising due to mutations in the isoform 2 of the sarco (endo) plasmic reticulum Ca 2+ ATPase (SERCA2), exemplifies an anomaly of Ca 2+ signaling disturbances. Owing to loss of function mutations in SERCA2, keratinocytes in" @default.
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- W2378620870 title "Visions & Reflections (Minireview) Dariers disease: a calcium-signaling perspective" @default.
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