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- W2378623284 abstract "Objective:To assess biological compatibility and absorption property of chitosan-collagen membrane.Methods:Five membranes of dried-chitosan,frozen-chitosan,chitosan-collagen compound membranes,chitosan-collagen composite and frozen-dried membranes were inserted in dorsal muscles of 36 rabbits.At 7,14,30,60,120 and 150 days,rabbits were sacrificed and histological observations were performed.In addition,biological degradation rate was calculated on day 30,60,90,120,150 and 180,compared with the dry weight of the membranes before and after implantation.Results:No obvious acute inflammation reaction was found in vivo.All membranes degraded slowly with no more than 20% absorbed in 3 months,while it was up to more than 50% in six months.Conclusion:The chitosan-collagen membranes have good biological compatibility and can remain intact in vivo for more than 3 months.Chatoyant-collagen can be used as guild bone regeneration membrane relying on its biological compatibility and degradation rate." @default.
- W2378623284 created "2016-06-24" @default.
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- W2378623284 date "2010-01-01" @default.
- W2378623284 modified "2023-09-28" @default.
- W2378623284 title "Research on biological compatibility and absorption property of absorbable chitosan-collagen membranes" @default.
- W2378623284 hasPublicationYear "2010" @default.
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