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- W2378626018 abstract "Objective: To explore the effect of active immune therapy on expression of Th1/Th2 mode in peripheral blood of patients with unexplained recurrent spontaneous abortion ( URSA) . Methods: Th1 /Th2 modes in peripheral blood in 30 patients with URSA before and after active immune therapy were detected by flow cytometry,30 normal fertilized women were selected as control group. Results: The level of interferon - γ ( IFN - γ) in Th1 cells of URSA group was ( 18. 98 ± 5. 37) % ,which was significantly higher than that of control group ( 8. 69 ± 2. 66) % ( P 0. 05) ; the level of interleukin - 4 ( IL - 4) in Th2 cells of URSA group was ( 5. 52 ± 0. 18) % ,which was significantly lower than that of control group ( 6. 78 ± 0. 61) % ( P 0. 05) ; the ratio of Th1 /Th2 was 3. 14,the mode migrated to Th1. After active immune therapy,the level of IL - 4 in Th2 cells was ( 10. 27 ± 2. 04) % ,and the level of IFN - γ in Th1 cells was ( 11. 73 ± 2. 47) % ; the ratio of Th1 /Th2 was 1. 41,the mode migrated to Th2. Conclusion: Th1 /Th2 mode of patients with URSA migrates to Th1, while Th1 /Th2 mode migrates to Th2 after active immune therapy,then immune tolerance of mothers and fetuses is induced,and success pregnancy is got." @default.
- W2378626018 created "2016-06-24" @default.
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- W2378626018 date "2010-01-01" @default.
- W2378626018 modified "2023-09-25" @default.
- W2378626018 title "Effect of active immune therapy on expression of Th1 /Th2 mode in peripheral blood of patients with recurrent spontaneous abortion" @default.
- W2378626018 hasPublicationYear "2010" @default.
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