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- W2378628283 abstract "Aim:To observe the effects of Chinese medicine soluble granule of Shengjing on spermatogenesis disturbance of mice.Methods:A total of 30 Kunming mice were randomly divided into 3 groups:control group,model group,and the Chinese medicine group. Spermatogenesis disturbance models were obtained by being intraperitoneally injected cyclophosphamide.In the Chinese medicine group,soluble granule of Shengjing was administered after the models were formed(16 g/(kg·d),15 d).Mice in model group and control group were gavaged with equivalent normal saline. Testis weight was measured, blood was collected and the follicle stimulating hormone (FSH),luteinizing hormone(LH), and testosterone(T) levels were measured by radioimmunoassay. The histologic changes of testis were observed by using microscopy.Results:There were no significant differences on FSH, LH, T levels, testis weight, and the number of sperm cells on the seminiferous tubules and the spermatozoon in the lumina of the seminiferous tubules in the Chinese medicine group compared with control group (P0.05), and there were significant differences on all index compared with model group (P0.05).Conclusion:The Chinese medicine soluble granule of Shengjing is effective for therapy of spermatogenesis disturbance." @default.
- W2378628283 created "2016-06-24" @default.
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- W2378628283 date "2008-01-01" @default.
- W2378628283 modified "2023-09-25" @default.
- W2378628283 title "Effects of soluble granule of Shengjing on spermatogenesis disturbance induced by cyclophosphamide in mice" @default.
- W2378628283 hasPublicationYear "2008" @default.
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