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- W2378628295 abstract "Objective To study the mechanism of Danshen injection in improving human erythrocyte deformability.Methods Healthy adults and the patients with hypertension were studied by the fluoresent _chelator fura_2 to examine the effect of Danshen injection on cytosolic free calcium concentration in intact erythrocytes in vitro.Results The cytosolic free calcium concentration in intact erythrocytes from the patients with hypertension is higher than that in healthy adults(P0.001). Danshen injection can decrease the cytosolic free calcium concentration of erythrocytes from both healthy adults and the patients with hypertension in vitro(P0.01),It shows dose_dependence and the effect has a positive correlation with the initial cytosolic free calcium concentration (P0.05). Conclusions Danshen injection may increase human erythrocyte deformability by decreasing the cytosolic free calcium concentration, which is effective to improve the microcirculation of patients with hypertension whose initial cytosolic free calcium concentration is higher than normal." @default.
- W2378628295 created "2016-06-24" @default.
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- W2378628295 date "2001-01-01" @default.
- W2378628295 modified "2023-09-25" @default.
- W2378628295 title "Effect of Danshen Injection on Cytosolic Free Calcium Concentration in Human Erythrocytes" @default.
- W2378628295 hasPublicationYear "2001" @default.
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