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- W2378628383 abstract "Aberrant activated Wnt signaling pathway plays a vital role in tumorigenesis and progression.Dickkopf-1(DKK-1),a member of Dickkopf family,is a secreted glycoprotein that acts as an extracellular antagonist of canonical Wnt signaling pathway.Recently,a number of studies have found that aberrant canonical Wnt pathway and DKK-1 implicate in the occurrence and development of cervical cancer.Anti-DKK-1 neutralizing antibody BHQ880,is currently in Phase Ⅰ/Ⅱ clinical trials for treating multiple myeloma.Here is to make a review on the research progress of the role of DKK-1 in cervical cancer,providing a new valuable biomarker in cancer detection,treatment and prognosis." @default.
- W2378628383 created "2016-06-24" @default.
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- W2378628383 date "2012-01-01" @default.
- W2378628383 modified "2023-09-26" @default.
- W2378628383 title "Research Progress in the Role of Wnt Signaling Pathway Antagonist Dickkopf-1 in Cervical Cancer" @default.
- W2378628383 hasPublicationYear "2012" @default.
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