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- W2378634822 abstract "OBJECTIVE To study protective effects of crocin on cultured calf aortic endothelial cells injured by low-density lipoproteins(LDL).METHODS Bovine aortic endothelial cells was incubated with crocin for 12 hours at different dosages,and then cultured with LDL for 24 h,the activity of LDH,NO in culture media and activity of NOS in endothelial cells were measured.The atherosclerosis formation was induced by hyperlipidamic diet,after the 9 weeks,the leves of serum LDL and NO were measured.RESULTS Compared with control,LDL group could decrease activity of NO in culture media and activity of NOS in endothelial cells.If endothelial cells was preincubated with crocin,the effects of LDL could be inhibited.Compared with the model group,crocin was reduce the level of LDL and elevation NO concentration.CONCLUSION It indicates that crocin has protective effects on cultured calf aortic endothelial cells injured by low-density lipoproteins." @default.
- W2378634822 created "2016-06-24" @default.
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- W2378634822 date "2006-01-01" @default.
- W2378634822 modified "2023-09-23" @default.
- W2378634822 title "Protective effects of crocin on cultured calf aortic endothelial cells injured by low-density lipoproteins" @default.
- W2378634822 hasPublicationYear "2006" @default.
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