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- W2378638950 abstract "Objective To screen and identify multiple myeloma-associated proteins in urine.Methods Collect the second morning urine of volunteers in MM group,disease control group(nephropathy) and healthy control group.Proteins were precipitated with TCA,and separated with two-dimensional polyacrylamide gel electrophoresis(2D-PAGE).After silver nitrate staining,proteins differential expression was analyzed by Image Master software and identified with MALDI-TOF-MS.Results 57 proteins that were differentially expressed in MM comparedwith control groups and 9 proteins were identified including Mbl-associated protein 19(Map19),Hla-A2,Retinol-binding protein(RBP),transthyretin(TTR),immunoglobulin light chain,alpha-2-glycoprotein 1(ZAG1) and so on.Conclusion Urinary proteomics is a successful tool to study the differentially expressed proteins,some of them might be the biomarkers of MM." @default.
- W2378638950 created "2016-06-24" @default.
- W2378638950 creator A5091021729 @default.
- W2378638950 date "2011-01-01" @default.
- W2378638950 modified "2023-09-23" @default.
- W2378638950 title "Preliminary analysis of screening multiple myeloma-associated proteins by urinary proteomics" @default.
- W2378638950 hasPublicationYear "2011" @default.
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