Matches in SemOpenAlex for { <https://semopenalex.org/work/W2378643016> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2378643016 abstract "AIM: To investigate the effect of ketamine,midazolam and propofol on intracellular Ca2+ in developing primary hippocampus neurons of rats.METHODS: On the fifth day,the cultured hippocampal neurons were co-incubated with 10 μmol/L Fluo-4 AM for 30 min at 37℃.Excess dye was removed with three rinses of DMEM.Fluorescence imaging of intracellular Ca2+ was performed to detect a number of neurons selected when the hippocampal neurons were exposed to 150 μmol/L ketamine,3 μmol/L midazolam or 10 μmol/L propofol respectively.RESULTS: After exposed to 150 μmol/L ketamine,the intracellular calcium concentration of the developing neurons decreased significantly and fluorescence intensity of the neurons decreased from(987±307) to(766±226)(P0.05).When exposed to 3 μmol/L midazolam or 10 μmol/L propofol,the cytosolic Ca2+ of the neurons increased significantly and fluorescence intensity of the neurons exposed to midazolam increased from(1707±514) to(2663±572)(P0.05).Fluorescence intensity of the neurons exposed to propofol increased from(1057±353) to(1749±708)(P0.05).CONCLUSION: Ketamine decreases the intracellular Ca2+ of rat developing primary hippocampus neurons while midazolam and propofol may increase the intracellular Ca2+ of the neurons." @default.
- W2378643016 created "2016-06-24" @default.
- W2378643016 creator A5023363460 @default.
- W2378643016 date "2009-01-01" @default.
- W2378643016 modified "2023-09-28" @default.
- W2378643016 title "Effect of ketamine,midazolam and propofol on intracellular Ca~(2+) in developing neurons" @default.
- W2378643016 hasPublicationYear "2009" @default.
- W2378643016 type Work @default.
- W2378643016 sameAs 2378643016 @default.
- W2378643016 citedByCount "0" @default.
- W2378643016 crossrefType "journal-article" @default.
- W2378643016 hasAuthorship W2378643016A5023363460 @default.
- W2378643016 hasConcept C12554922 @default.
- W2378643016 hasConcept C134018914 @default.
- W2378643016 hasConcept C148762608 @default.
- W2378643016 hasConcept C181080969 @default.
- W2378643016 hasConcept C181199279 @default.
- W2378643016 hasConcept C185592680 @default.
- W2378643016 hasConcept C2776277131 @default.
- W2378643016 hasConcept C2776814716 @default.
- W2378643016 hasConcept C2778000748 @default.
- W2378643016 hasConcept C2780795376 @default.
- W2378643016 hasConcept C2781161787 @default.
- W2378643016 hasConcept C42219234 @default.
- W2378643016 hasConcept C55493867 @default.
- W2378643016 hasConcept C71924100 @default.
- W2378643016 hasConcept C79879829 @default.
- W2378643016 hasConcept C86803240 @default.
- W2378643016 hasConcept C98274493 @default.
- W2378643016 hasConcept C98539663 @default.
- W2378643016 hasConceptScore W2378643016C12554922 @default.
- W2378643016 hasConceptScore W2378643016C134018914 @default.
- W2378643016 hasConceptScore W2378643016C148762608 @default.
- W2378643016 hasConceptScore W2378643016C181080969 @default.
- W2378643016 hasConceptScore W2378643016C181199279 @default.
- W2378643016 hasConceptScore W2378643016C185592680 @default.
- W2378643016 hasConceptScore W2378643016C2776277131 @default.
- W2378643016 hasConceptScore W2378643016C2776814716 @default.
- W2378643016 hasConceptScore W2378643016C2778000748 @default.
- W2378643016 hasConceptScore W2378643016C2780795376 @default.
- W2378643016 hasConceptScore W2378643016C2781161787 @default.
- W2378643016 hasConceptScore W2378643016C42219234 @default.
- W2378643016 hasConceptScore W2378643016C55493867 @default.
- W2378643016 hasConceptScore W2378643016C71924100 @default.
- W2378643016 hasConceptScore W2378643016C79879829 @default.
- W2378643016 hasConceptScore W2378643016C86803240 @default.
- W2378643016 hasConceptScore W2378643016C98274493 @default.
- W2378643016 hasConceptScore W2378643016C98539663 @default.
- W2378643016 hasOpenAccess W2378643016 @default.
- W2378643016 hasRelatedWork W2313822522 @default.
- W2378643016 hasRelatedWork W2338748116 @default.
- W2378643016 hasRelatedWork W2402126984 @default.
- W2378643016 hasRelatedWork W2406011626 @default.
- W2378643016 hasRelatedWork W2411827009 @default.
- W2378643016 hasRelatedWork W2468483348 @default.
- W2378643016 hasRelatedWork W2588976752 @default.
- W2378643016 hasRelatedWork W2590448289 @default.
- W2378643016 hasRelatedWork W2742965967 @default.
- W2378643016 hasRelatedWork W2978670284 @default.
- W2378643016 hasRelatedWork W3028686639 @default.
- W2378643016 hasRelatedWork W3029430042 @default.
- W2378643016 hasRelatedWork W3029749405 @default.
- W2378643016 hasRelatedWork W3031577667 @default.
- W2378643016 hasRelatedWork W3031817131 @default.
- W2378643016 hasRelatedWork W3032763060 @default.
- W2378643016 hasRelatedWork W3029251831 @default.
- W2378643016 hasRelatedWork W3029390757 @default.
- W2378643016 hasRelatedWork W3030706529 @default.
- W2378643016 hasRelatedWork W3032129977 @default.
- W2378643016 isParatext "false" @default.
- W2378643016 isRetracted "false" @default.
- W2378643016 magId "2378643016" @default.
- W2378643016 workType "article" @default.