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- W2378645799 abstract "The experiments by using 45Ca were performed to investigate Ca2+ transfer of the liver subcellular fraction in the male aged Wistar rats (24-month-old) and the effects of thymic factor D (TFD), extracted from the pig thymus, on these parameters. It was found in the aged rats that Ca2+ uptake of the liver microsome and mitochondria showed a significant decrease, with a simultaneous increase inthe passive Ca2+ release from the liver microsome. TFD, given to the aged rats, at a dose of 2 mg·kg-1 sc every other day for 3 month increased Ca2+ uptake of the liver microsome and decreased the passive Ca2+ release from the liver microsome, showing a beneficial effect on maintaining intracellular calcium homeostasis. In addition, TFD reversed an increase of lipid peroxides and a decrease of membrane fluidity in the liver microsome and mitochondria of the aged rats" @default.
- W2378645799 created "2016-06-24" @default.
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- W2378645799 date "1992-01-01" @default.
- W2378645799 modified "2023-09-23" @default.
- W2378645799 title "Effects of thymic factor D on Ca~(2+) transfer of liver microsome and mitochondria in aged rats" @default.
- W2378645799 hasPublicationYear "1992" @default.
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