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- W2378660601 abstract "GDF11,also known as bone morphogenetic protein 11(BMP11),is a member of the transforming growth factor-β superfamily and BMPs subfamily.It is a secreted protein which is considered to be a key regulator of axial skeleton patterning during early embryogenesis.In this study,the partial cDNA of porcine GDF11 gene was cloned by RT-PCR and the expression patterns of GDF11 gene were detected.Sequence analysis indicates that the sequences of porcine GDF11 gene were 1161 bp in length(GenBank:HQ657211.2).The cloned cDNA encoded a protein of 332 amino acid residues,which shared 99.10%,99.10%,99.10%,99.40%,99.10%,98.80% and 78.82% identity with those of human,mouse,rat,cattle,horse,rabbit and zebra fish,respectively.Expression patterns of GDF11 were detected in 14 different tissues by real time quantitative RT-PCR,and patterns of GDF11 gene,as a whole,tended to be spinal cordbackfaturinary bladderlungspleengallbladderkidneylarge intestineheartskeletal muscleliversmall intestinelongissimus Dorsi musclestomach.These results provide important information for further elucidating the molecular biology functions and mechanism of GDF11 gene." @default.
- W2378660601 created "2016-06-24" @default.
- W2378660601 creator A5056029165 @default.
- W2378660601 date "2012-01-01" @default.
- W2378660601 modified "2023-09-23" @default.
- W2378660601 title "Molecular Cloning and Expression Patterns of GDF11 Gene in Licha Black Pig" @default.
- W2378660601 hasPublicationYear "2012" @default.
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