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- W2378662926 abstract "OBJECTIVE To study the antiarrhythmic effect of extracts of Valeriana officinalis.METHODS The arrhythmic animal models were respectively performed by aconitine(rats)and trichloromethane(mice).The treatment groups were given with the extracts of Valeriana officinalis,the positve-effect drug treatment group gained lidocaine(rats)or propranolol(mice),and the control group gained only normal saline.Make a comparison among the arrhythmic pictures in all groups.RESULTS Water-extracts of Valeriana officinalis L.could markedly delay the occurring time of ventricular extrasystole,ventricular fibrillation(VF)caused by aconitine in rats;reduce the ratio of VF,P0.01;.n-BuOH extracts could markedly delay the occurring time of ventricular extrasystole,ventricular fibrillation(VF)caused by aconitine in rats;and reduce the ratio of VF,P0.05;essential oil of Valeriana officinalis L could markedly reduce the ratio of VF caused by trichloromethane in mice,P0.01;.ethyl acetate extract of Valeriana officinalis L could markedly reduce the ratio of VF,P0.05(comparing with positive drags,).CONCLUSION The water-extract is the most effective of the extracts of Valeriana officinalis L.on cardiac arrhythmias." @default.
- W2378662926 created "2016-06-24" @default.
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- W2378662926 date "2009-01-01" @default.
- W2378662926 modified "2023-09-23" @default.
- W2378662926 title "Effect of the extracts of Valeriana officinalis L. on cardiac arrhythmias" @default.
- W2378662926 hasPublicationYear "2009" @default.
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