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- W2378745967 abstract "Objective To study the specificity of the serotype-specific IgG in the sera of patients with chronic pulmonary diseases(CPD)after pneumococcal vaccination.Methods Serotype-specific IgG concentrations were measured by the second and third(with more specificity)generation ELISA for serotype 6B,19F and 23F in 39 CPD patients after vaccinated with 23-valent pneumococcal polysaccharide vaccine(PPV).Results The serotype-specific IgG levels measured by the third-generation ELISA were much lower than those by the second-generation ELISA.About half of the anti-CPS IgG in the sera of CPD patients was non-specific antibody whether natural infection or vaccination.Conclusion PPV can not improve the proportion of serotype-specific antibodies in the sera of patients with CPD." @default.
- W2378745967 created "2016-06-24" @default.
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- W2378745967 date "2010-01-01" @default.
- W2378745967 modified "2023-09-26" @default.
- W2378745967 title "Specificity of antibody response to 23-valent pneumococcal polysaccharide vaccine in patients with chronic pulmonary diseases" @default.
- W2378745967 hasPublicationYear "2010" @default.
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