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- W2378882009 abstract "Cutaneous and mucosal epithelial cells are a physical barrier and the first defense line of host against environmental changes.The crosstalk between epithelial cells,dendritic cells(DCs) and leukocytes play an important role in inducing proper immune responses during host defense.Interleukin-17(IL-17) family cytokines are cytokines discovered recently,playing important roles as powerful pro-inflammatory cytokines.They are important players in innate and adaptive immune response of host.IL-17A,IL-17C and IL-17F can directly target tissue epithelial cells to induce various antimicrobial responses against extracellular pathogens and promote tissue remodeling.By contrast,IL-17E primarily acts on leukocytes and induces type Ⅱ immunity that is crucial for protection against parasites.IL-17E also negatively regulates IL-17A and IL-17F production from leukocytes while reports are less on IL-17B and IL-17D." @default.
- W2378882009 created "2016-06-24" @default.
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- W2378882009 date "2013-01-01" @default.
- W2378882009 modified "2023-09-27" @default.
- W2378882009 title "Research Progress on Regulation Mucosal Immune of IL-17 Cytokine Family" @default.
- W2378882009 hasPublicationYear "2013" @default.
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