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- W2378934626 abstract "Objective To explore the changes and significance of c-fos after severe burn with delayed fluid resuscitation.Methods A total of 96 male SD rats were employed as the experimental models(TBSA 30%,grade Ⅲ),and they were randomly divided into 3 groups:delayed fluid resuscitation group(DF),immediate fluid resuscitation group(IF)and normal control group(NC).The lung samples were harvested at 1,6,12,24,72 and 168 h after burn respectively.Pathological changes of lung tissue and c-fos expression were detected by using histopathology,immunohistochemistry and image analysis techniques.Results Postburn 6-24 h,the pathological changes of lung tissue were more severe in DF group than those in IF group.c-fos were much higher in DF group and IF group than those in NC group(P0.05).The increase of c-fos was observed in nucleus and cytoplasm.Conclusions The result indicates that c-fos may contribute significantly to lung injury following severe burn with delayed fluid resuscitation in rats." @default.
- W2378934626 created "2016-06-24" @default.
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- W2378934626 date "2011-01-01" @default.
- W2378934626 modified "2023-09-28" @default.
- W2378934626 title "Expression and significance of c-fos in lung tissue after severe burn with delayed fluid resuscitation in rats" @default.
- W2378934626 hasPublicationYear "2011" @default.
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