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- W2378936550 abstract "Objective To explore the changes of serum adiponectin in septic patients,and the relations between adiponectin and insulin resistance (IR),C-reactive protein (CRP).Methods Forty-five septic patients and 20 healthy controls subjects were enrolled.Fasting blood glucose (FBG),fasting insulin (FINS),CRP and adiponectin were determined on the 1st,5th and 10th d after diagnosed as sepsis among patients.Insulin resistance (IR) index was estimated by homeostasis model assessment (HOMA).Results The mean serum adiponectin concentrations in septic patients on the 1st,5th and 10th d were (4.82±3.29),(5.15±3.41),and (4.97±3.21) μg/ml,respectively,and showed no significantly difference,P0.05.However,these were lower than the serum adiponectin in the control group [(8.81±2.70) μg/ml],all P 0.01.Serum adiponectin was negatively correlated with BMI,FBG,FINS,HOMA-IR,and acute physiology and chronic health evaluation (APACHE) Ⅱ scores.No significant correlation was found between adiponectin and CRP.Conclusion The serum adiponectin level is significantly decreased in septic patients,and adiponectin is negatively correlated with HOMA-IR and APACHE Ⅱscores." @default.
- W2378936550 created "2016-06-24" @default.
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- W2378936550 date "2010-01-01" @default.
- W2378936550 modified "2023-09-24" @default.
- W2378936550 title "Preliminary study on changes of serum adiponectin concentrations in patients with sepsis" @default.
- W2378936550 hasPublicationYear "2010" @default.
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