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- W2379005665 abstract "Objective: To evaluate the biomechanical efficacy of calcium phosphate cement(CPC) in augmentation and restoration of fusion equipment of pedicle of vertebrae(FEPV).Methods: Ten fresh lumbar vertebrae of eight adult cadavers were employed in this experiment.Twenty out of 32 specimens were randomly divided into three groups(A,B,C),each group included ten vertebrae(L1 to L4).Group A(control group):The FEPV were implanted into the pedicle bilateral.The FEPV were not penetrated the anterior cortex of the vertebral bodies.The FEPV were pulled out from the vertebrae at 5 mm/min.Group B(restoration group):The bilateral FEPV track were filled with 3 to 5 ml of CPC).Then,the FEPV were implanted bilaterally,and the CPC was allowed to harden for 1 hour under room temperature(28 ℃),then pull out test was employed.Group C(reinforcement group): The bilateral FEPV track were directly filled with 3 to 5 ml of CPC.Then pull out test was employed again.Morphology of CPC around the FEPV was observed by section of the vertebrae along the FEPV.Group B: In the remaining 10 specimens,the FEPV were loaded in the superior-inferior direction with increasing forces of 25 to 200 N for 800 cycles.Results: The pull out strength of the FEPV in control group was(843.1±132.2) N,whereas those following CPC restoration and CPC augmentation were(1 456.2±239.9) N and(1 499.5±241.2) N respectively.The pull out strength following CPC restoration and augmentation were significantly greater than that of control group(P0.05).No CPC was found in vertebral canal or surface of pedicle in the FEPV.In cyclic bending resistance tests,augmented the FEPV was found to withstand a greater number of cycles or greater loading(200 N,800 cycles) before loosening.Conclusion: Restoration and augmentation with CPC offered a significantly increase of strength for the FEPV fixation,and it can decrease spill in vertebral canal or surface of pedicle.Cells of bone were easily implanted into lateral hole of the FEPV without CPC.It can increase stability of the FEPV too,and can be used clinically in case of failure of pedicle screw fixation." @default.
- W2379005665 created "2016-06-24" @default.
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- W2379005665 date "2007-01-01" @default.
- W2379005665 modified "2023-09-23" @default.
- W2379005665 title "Augmentation of fusion equipment of pedicle of vertebrae with calcium phosphate cement:An in vitro biomechanical study" @default.
- W2379005665 hasPublicationYear "2007" @default.
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