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- W2379022411 abstract "Objective To explore the expression and distribution of H2-Calponin mRNA and protein in four cancerous tissues and its clinical significance.Methods In situ RT-PCR was used to detect the expression and distribution of H2-Calponin mRNA in four different cancerous tissues.Immunohistochemistry was used to detect the expression of H2-Calponin protein in lung cancer,gastric carcinoma,nasopharyngeal carcinoma(NPC) and hepatocellular carcinoma(HCC).Results H2-Calponin protein was mainly expressed in cytoplasm by immunohistochemistry.The positive rates of H2-calponin protein in lung cancer,gastric carcinoma,nasopharyngeal carcinoma and HCC were 30.0%,27.5%,45.0% and 51.8%,respectively.The expression positive rate of H2-Calponin in HCC was the highest.The expression of H2-Calponin mRNA was showed near the nucleus by in situ RT-PCR.The mRNA expression rates of H2-Calponin in lung cancer,gastric carcinoma,nasopharyngeal carcinoma and HCC were 17.5%,10.0%,20.0% and 50.0%,respectively.The positive rate was the highest H2-Calponin in HCC.The positive rate of H2-calponin protein in HCC with metastasis was higher than that without metastasis.The expression of H2-Calponin protein in four different cancerous tissues was not statistically different with patient gender,age and pathologic differentiation grade.Conclusions H2-Calponin protein is correlated with HCC,specially positively correlated with HCC with metastasis." @default.
- W2379022411 created "2016-06-24" @default.
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- W2379022411 date "2013-01-01" @default.
- W2379022411 modified "2023-09-26" @default.
- W2379022411 title "Expression of H2-Calponin protein in four cancerous tissues and its clinical significance" @default.
- W2379022411 hasPublicationYear "2013" @default.
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