FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2379046950> ?p ?o ?g. }

• W2379046950 endingPage "782" @default.
• W2379046950 startingPage "782" @default.
• W2379046950 abstract "Objective About 20-50% indiv iduals with intrauterine growth retardation (IUGR) could not achieve catch-up g rowth and remain small in size till adulthood. There are few reports on the rel ation between intestinal development and body catch-up growth of IUGR. Studies showed that early programming would results in long-term eff ects on the body growth and organic function, and gastrointestinal development i s closely related to the body development as well. The authors aimed to study t he effect of early nutritional interventions on serum IGF1, IGFBP3, intestinal d evelopment and catch-up growth of pups with IUGR by using diets with different protein and caloric levels during the first four weeks of life. Meth ods An IUGR rat model was established by maternal nutrition restri ction during pregnancy. Thirty-two IUGR female pups were divided randomly into 4 groups(8 pups in each group)and eight normal female pups as control. The groups and interventions were (1) Normal control group(C group); (2) IUGR contro l group(S group), (3) IUGR low-protein diet group(SL group); (4) IUGR high-pro tein diet group (SH group); (5) IUGR high-caloric group( SA group). The serum IGF1, IGFBP3, body weight, body length, and intestinal weight, length, intestina l villi height(VH), crypt depth(CD), villi absorbing area(VSA), mucous thickness (MT) were measured atthe 4 th week of life. Results (1) At the 4 th week, the serum IGF1 (724.0±153.5 ng/ml), IGFBP3 (9.6 9±3.13 ng/ml),and VH (416.9±46.3 μm), VSA (115.9±24.0×103μm2), MT (583.9±68.5 μm) in the SH group were significantly higher than those of no rmal control group (539.4±198.4 ng/ml, 4.77±2.98 ng/ml and 322.1±25.8 μm, 85.8±17.8×103μm2, 480.0±61.5 μm) and IUGR control group(P 0.05). The intestinal weight (1.91±0.16 g) and length (80.67±9.47 cm) in the SH group was not significantly different from the normal control group (2. 24±0.22 g and 74.77±9.06 cm, P0.05). The SH group showed the fastest catch-up growth. Their body weights (40.14±11.03 g) at the 3 rd week and body lengths (23.61±0.49 cm) atthe 4 th week of life reached the no rmal ranges of the control group (44.65±5.36 g and 23.10±1.42 cm, P0 .05). (2) The serum IGF1 (346.7±85.3 ng/ml), IGFBP3 (1.4±0.21 ng/ml), bo dy weight (21.41±3.54 g) and body length ( 15.96±1.29 cm) and the most of intestinal indexes in the SL group were markedly lower than other groups at t he 4 th week of life (P0.05). Conclusion The serum IGF1 was a sensitive marker to reflect the catch-up growth and nutritiona l status, and IGF1 was positively correlated with the intestinal development and body growth. When given different nutritional interventions during the first f our weeks of life, high protein diet is more helpful for the IUGR catch-up grow th by promoting the intestinal development and the absorption of nutrition." @default.
• W2379046950 created "2016-06-24" @default.
• W2379046950 creator A5000919272 @default.
• W2379046950 creator A5021421303 @default.
• W2379046950 creator A5038031221 @default.
• W2379046950 creator A5052936351 @default.
• W2379046950 creator A5084599388 @default.
• W2379046950 creator A5086310450 @default.
• W2379046950 creator A5087320056 @default.
• W2379046950 date "2004-10-01" @default.
• W2379046950 modified "2023-09-25" @default.
• W2379046950 title "[Effect of different early nutritional interventions on catch-up growth of rats with intrauterine growth retardation]." @default.
• W2379046950 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16221353" @default.
• W2379046950 hasPublicationYear "2004" @default.
• W2379046950 type Work @default.
• W2379046950 sameAs 2379046950 @default.
• W2379046950 citedByCount "0" @default.
• W2379046950 crossrefType "journal-article" @default.
• W2379046950 hasAuthorship W2379046950A5000919272 @default.
• W2379046950 hasAuthorship W2379046950A5021421303 @default.
• W2379046950 hasAuthorship W2379046950A5038031221 @default.
• W2379046950 hasAuthorship W2379046950A5052936351 @default.
• W2379046950 hasAuthorship W2379046950A5084599388 @default.
• W2379046950 hasAuthorship W2379046950A5086310450 @default.
• W2379046950 hasAuthorship W2379046950A5087320056 @default.
• W2379046950 hasConcept C126322002 @default.
• W2379046950 hasConcept C134018914 @default.
• W2379046950 hasConcept C147583825 @default.
• W2379046950 hasConcept C170493617 @default.
• W2379046950 hasConcept C2775960820 @default.
• W2379046950 hasConcept C2778279177 @default.
• W2379046950 hasConcept C2779234561 @default.
• W2379046950 hasConcept C3020705096 @default.
• W2379046950 hasConcept C42407357 @default.
• W2379046950 hasConcept C54355233 @default.
• W2379046950 hasConcept C71924100 @default.
• W2379046950 hasConcept C86803240 @default.
• W2379046950 hasConceptScore W2379046950C126322002 @default.
• W2379046950 hasConceptScore W2379046950C134018914 @default.
• W2379046950 hasConceptScore W2379046950C147583825 @default.
• W2379046950 hasConceptScore W2379046950C170493617 @default.
• W2379046950 hasConceptScore W2379046950C2775960820 @default.
• W2379046950 hasConceptScore W2379046950C2778279177 @default.
• W2379046950 hasConceptScore W2379046950C2779234561 @default.
• W2379046950 hasConceptScore W2379046950C3020705096 @default.
• W2379046950 hasConceptScore W2379046950C42407357 @default.
• W2379046950 hasConceptScore W2379046950C54355233 @default.
• W2379046950 hasConceptScore W2379046950C71924100 @default.
• W2379046950 hasConceptScore W2379046950C86803240 @default.
• W2379046950 hasIssue "10" @default.
• W2379046950 hasLocation W23790469501 @default.
• W2379046950 hasLocation W23790469502 @default.
• W2379046950 hasOpenAccess W2379046950 @default.
• W2379046950 hasPrimaryLocation W23790469501 @default.
• W2379046950 hasRelatedWork W1979890350 @default.
• W2379046950 hasRelatedWork W1981302871 @default.
• W2379046950 hasRelatedWork W2018269745 @default.
• W2379046950 hasRelatedWork W2022737278 @default.
• W2379046950 hasRelatedWork W2076450635 @default.
• W2379046950 hasRelatedWork W2319534541 @default.
• W2379046950 hasRelatedWork W2333846687 @default.
• W2379046950 hasRelatedWork W2393238415 @default.
• W2379046950 hasRelatedWork W2398835055 @default.
• W2379046950 hasRelatedWork W2404998000 @default.
• W2379046950 hasRelatedWork W2415015262 @default.
• W2379046950 hasRelatedWork W2955250624 @default.
• W2379046950 hasRelatedWork W3016525554 @default.
• W2379046950 hasRelatedWork W3024523005 @default.
• W2379046950 hasRelatedWork W3029133930 @default.
• W2379046950 hasRelatedWork W3030814267 @default.
• W2379046950 hasRelatedWork W3030856808 @default.
• W2379046950 hasRelatedWork W3031043191 @default.
• W2379046950 hasRelatedWork W3031505697 @default.
• W2379046950 hasRelatedWork W3032137277 @default.
• W2379046950 hasVolume "42" @default.
• W2379046950 isParatext "false" @default.
• W2379046950 isRetracted "false" @default.
• W2379046950 magId "2379046950" @default.
• W2379046950 workType "article" @default.