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- W2379079100 abstract "Objective:To determine the expression of estrogen receptor α and estrogen receptor β (ERα、ERβ) in the endometrium of rats with polycystic ovary syndrome(PCOS). Methods: PCOS model was made by dehydroepiandrosterone(DHEA)and insuline(n=30). The serum hormone levels were examined by radioimmunoassay. The expression of the mRNA and protein of ERα and ERβ in endometrium of twogroups were observed by using reverse transcription polymerase chain reaction(RT-PCR)and immunohistochemistry. Results: The expression of protein of ERα in PCOS group in endometrium was significantly higher than those in the control group(P0.01); whereas,the expression ofprotein ofERβ in endometriumwas not significantlydifferent between the twogroups(P0.05). RT-PCR analysis showed the same expression of ERα mRNA and ERβ mRNA in endometrium as immunohistochemistry. Conclusion: ERα in endometrium of PCOS rats is expressed excessively." @default.
- W2379079100 created "2016-06-24" @default.
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- W2379079100 date "2009-01-01" @default.
- W2379079100 modified "2023-09-24" @default.
- W2379079100 title "Expression and significance of estrogen receptor α and β in endometrium of rats with polycystic ovary syndrome" @default.
- W2379079100 hasPublicationYear "2009" @default.
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