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- W2379123387 abstract "AIM To reveal the influence of electro acupuncture (EA) both on the contents of substance P in centrum and peripheral blood and on its immune function in rats. METHODS The SD rats were divided into five groups, including control group, Zusanli group, immunosuppressive model group, none point group and immunosuppressive model+EA group. The contents of ir SP in centrum and peripheral blood were determined by Radioimmunoassay. Also T lymphocyte subgroups of peripheral blood (including CD 4 + and CD 8 +) were measured by direct microvolume whole blood immunoflurescent staining technique with flow cytometry (FCM) and erythrocyte immune function (including RBC C 3b RR and RBC ICR) were observed to evaluate the immune functions of rats from different aspects. RESULTS ①The contents of ir SP in centrum and peripheral blood, the value of CD 4 +, RBC C 3b RR and RBC ICR in EA group were significantly higher than those of control group ( P 0.01), and the value of CD 8 + was not statistically different between two groups. ②The variation of CD 4 + was significantly related with RBC C 3b RR ( r =0.744, P 0.05; r =0.738, P 0.05; r =0.719, P 0.05). ③ The contents of ir SP ( P 0.01)in centrum and peripheral blood, the value of CD 4 + ( P 0.05) and RBC C 3b RR ( P 0.01) in immunosuppressive model group were observably lower than those of control group, and the value of CD 8 + was not statistically different between two groups( P 0.05), which indicated that CY restrained the T lymphocyte subgroups of peripheral blood and erythrocyte immune function. ④ In immunosuppressive model+EA group, there was no marked difference as compared with control group ( P 0.05), while there was statistical difference as compared with immunosuppressive model group ( P 0.01 ). ⑤The date of the non Tsusanli group was not different from control group ( P 0.05). CONCLUSION When EA improves cellular immunity induced by T lymphocyte and red blood cell immune adherence function, the contents of ir SP in centrum and peripheral blood are improved markedly, which may have important significance in the clinical therapy with acupuncture." @default.
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- W2379123387 date "2001-01-01" @default.
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- W2379123387 title "Regulatory effects of electro acupuncture at Tsusanli on ir SP contents in rats' pituitary gland and peripheral blood and their immunity" @default.
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