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- W2379216779 abstract "Objective: To study the anti-tumor activity and effect of Shemmai liquid on glycometabolism(Radix Ginseng, Radix Ophiopogonis). Methods: On the basis of the model of Pixu rats bearing S 180and EAC solid carcinoma, The rats treated by different doses of Shenmai Injection, Cytoxan and normal saline, were observed by the tumor growth/inhibiting rate, LDH enzyme activity, and ultrastructure of cell under the electron microscope on the level of the whole animal. Results: For rats bearing S 180 , the inhibiting rates of different doses of Shenmai Injection groups were 54.17%, 38.42%, 31.02%, respectively. For rats bearing EAC solid carcinoma, the inhibiting rates of different doses of Shenmai injection were 56.04%, 43.6% and 34.8%, respectively. For the levels of LDH 1, there was no difference among the different doses of Shenmai Injection group and the control group of the rats bearing S 180and EAC solid carcinoma(P0.05). But the LDH 5 and LDH 5/LDH 1 of difference doses of Shenmai Injection group was lower than that of the control group obviously(P0.05). Conclusion: Shenmai Injection has obvious inhibitory effect on growth of the tumor cells in rats bearing S 180and EAC solid carcinoma, and its effect is correlated with the doses. Shenmai Injection can reduce the level of LDH 5/LDH 1 in tumor cells, to inhibit the glucolysis, all this may be one of the anti-tumor mechanism of the Shenmai Injection." @default.
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- W2379216779 date "2003-01-01" @default.
- W2379216779 modified "2023-09-23" @default.
- W2379216779 title "Experimental study of the anti-tumor activity and effect of Shenmai Liquid on glycometabolism" @default.
- W2379216779 hasPublicationYear "2003" @default.
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