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- W2379219962 abstract "Objective To study the changes in levels of androgen receptor ( AR) in patients with hepatocellular carcinoma.Methods Radioligand binding assay (RBA) was adopted to measure the androgen receptor ( AR) in cancer tissue and adjacent non-tumor tissue and peripheral blood leucocytes in 36 patients with hepatocellular carcinoma.Hormone radiloimmunoassay(RIA) was performed to determine serum testosterone level in patients and normal subjects.Results (1) The content of AR in the tumor samples was significantly higher than that in the surrounding non-tumor liver tissue(P0.01),and had a relationship with the size of the tumor; (2)The content of AR in the high differentiated phenotype was higher than that in the less differentiated phenotype(P0.01); (3)The level of serum testosterone in patients was slightly elevated (P0.05),but the content of AR in leucocytes was significantly increased(P0.01).Conclusion The occurrence of hepatocellula carcinoma is probably correlated with higher content of AR,whereas the content of AR is related to the size and differentiation degree of the tumor" @default.
- W2379219962 created "2016-06-24" @default.
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- W2379219962 date "2004-01-01" @default.
- W2379219962 modified "2023-09-25" @default.
- W2379219962 title "Clinicopathological study on expression of androgen receptor in hepatocellular carcinoma" @default.
- W2379219962 hasPublicationYear "2004" @default.
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