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- W2379244191 abstract "Objective To observe the character of the sleep and to detective the levels of motilin and somatostatin in patients with insomnia and constipation-predominant irritable bowel syndrome(C-IBS).Methods Data of 12 patients with insomnia and C-IBS,12 patients only with insomnia and 8 normal volunteers were collected.Patients slept one night in the sleep laboratory and monitored by polysomnography to determine sleep patterns.Motilin and somatostain were detected by radioimmunoassay in the next morning.Results Total sleep time,total SWS(slow wave sleep),percentage SWS,total REM time,sleep efficiency in patients with insomnia and/or without constipation were significantly lower than those in the normal volunteers.There was no significant difference in total sleep time,total REM time and percentage REM among three groups.The levels of the motilin in the patients with insomnia and constipation were significantly higher than that in the normal volunteers(271.89 pg/mL±51.25 pg/mL vs 240.85 pg/mL±41.41 pg/mL,P0.05),but the levels of the motilin were lower than that in the patients with insomnia without constipation(315.49 pg/mL±19.32 pg/mL).The levels of the somatostain in the patients with insomnia and constipation were significantly higher than that in the normal volunteers(505.49 pg/mL±30.49 pg/mL vs 438.32 pg/mL±23.67 pg/mL,P0.05).Conclusion Insomnia is related with C-IBS.Patients with insomnia and constipation had significantly higher levels in motilin and somatostain than the normal volunteers." @default.
- W2379244191 created "2016-06-24" @default.
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- W2379244191 date "2009-01-01" @default.
- W2379244191 modified "2023-09-26" @default.
- W2379244191 title "The clinical observation on sleep character,and levels of motilin and somatostatin in patients with insomnia and constipation-predominant irritable bowel syndrome" @default.
- W2379244191 hasPublicationYear "2009" @default.
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