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- W2379394871 abstract "Objective To explore the relationship between the level of plasma homocysteine (Hcy) and the damage of vascular endothelial cell in patients with acute myocardial infarction (AMI). Methods The levels of plasma Hcy,von willebrand factor (VWF) and C-reaction protein (C-RP) in 62 AMI patients and 48 healthy controls were detected respectively by enzyme-linked im- munosorbent assay and immune turbidimetry.The damage of vascular endothelial cells of arteria coronaria was observed by electron microscopy.Results The level of plasma Hcy was significantly higher in AMI patients than in healthy controls and the levels of VWF and C-RP were also sig- nificantly higher in AMI patients than in healthy controls (P0.01).The multi-factors related analysis showed that Hcy had significant correlation with C-RP and VWF.Electron microscopy revealed that VECs were damaged significantly in artery.Conclusion Hcy is an independent risk factor of AMI,which might cause and deteriorate AMI by injuring vascular endothelial cells. It might be helpful to detect the level of Hcy at the early stage of AMI for AMI treatment." @default.
- W2379394871 created "2016-06-24" @default.
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- W2379394871 date "2007-01-01" @default.
- W2379394871 modified "2023-09-24" @default.
- W2379394871 title "Relationship between the level of plasma homocysteine and the damage of vascular endothelial cell in patients with acute myocardial infarction" @default.
- W2379394871 hasPublicationYear "2007" @default.
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