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- W2379432924 abstract "Objective To evaluate the different diagnostic values of galactomannan( GM) in blood,sputum and bronchoalveolar lavage fluid( BALF) for the invasive pulmonary aspergillosis( IPA). Methods One hundred cases of COPD patients,including 43 IPA cases,57 non-IPA cases,were collected to conduct semi-quantitative determination of GM antigen in sputum, BALF and serum,and the different diagnostic efficiency of GM antigen for IPA were compared among sputum,BALF and serum. Results The OD values of GM in sputum,BALF and serum of COPD patients accompanying by IPA secondary infection were all significantly higher than those without IPA. When taking 0. 5 as the positive cutoff value,the sensitivity,specificity, positive predictive value and negative predictive values of GM in sputum,BALF and serum were 74. 4%,82. 4%,76. 2%, 81. 0%; 83. 7%,87. 7%,83. 7%,87. 7%; 48. 8%,94. 7%,87. 5%,71. 1%. When taking 1. 0 as the positive cutoff value,the specificity and positive predictive values of GM in BALF and serum were both 100%. However,the specificity of GM in sputum was 91. 2%. The sensitivity and negative predictive values of GM in BALF and sputum were both significantly higher than those in serum. Conclusion When taking 0. 5 as the positive cutoff value,GM in sputum and BLAF showed the similar diagnostic value for IPA in COPD patients,slightly better than serum and without pain due to invasive procedures,so galactomannan detection in sputum can be popularized." @default.
- W2379432924 created "2016-06-24" @default.
- W2379432924 creator A5031053572 @default.
- W2379432924 date "2014-01-01" @default.
- W2379432924 modified "2023-09-28" @default.
- W2379432924 title "The diagnosis value of galactomannan for invasive pulmonary aspergillosis in COPD patients" @default.
- W2379432924 hasPublicationYear "2014" @default.
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