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- W2379632999 abstract "Objective:To investigate the wide tropism of hepatitis B and C virus(HBV?HCV).Methods:Seventy-two patients were selected, among them 28 with chronic hepatitis B (chronic hepatitis B group), 44 with hepatitis B associated with cirrhosis (cirrhosis group); 30 patients with gastritis but without liver disease were used as control. In all patients diagnostic endoscopoy was performed. Two gastric biopsied were taken within 3 cm around the pylorus of gastric antra. Urease detection, HE, and immunohistochemical analysis of HBV and HCV antigen were conduted. Results:Different extent of chronic inflammation in cirrhosis group most patients with gland atrophy and intestinal metaplasia. The positivity of HBVAg in these two groups was 81.8%(36/44)?53.6%(15/28), respectively (P0.05). The positivity of HCVAg in 51 patients with chronic liver disease is 64.7%(33/51).Conclusion: There are obvious expression of HBV antigen in the gastric mucosa of patients with chronic liver disease and cirrhosis. Its role in the pathogenesis of gastric mucosal lesion is the worthful subject to be further studied." @default.
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- W2379632999 date "2004-01-01" @default.
- W2379632999 modified "2023-09-24" @default.
- W2379632999 title "Clinical Significance of Hepatitis B and C Virus Antigen Expression in Gastric Mucosa of Patients with Chronic Liver Disease" @default.
- W2379632999 hasPublicationYear "2004" @default.
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