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- W2379640269 abstract "Objective To study the bleeding volume,platelets function and hemostatic effect of reptilase in neurosurgery operations.Methods 120 patients scheduled for craniotomy were randomly divided into 2 groups to receive either normal saline as control(n=60)or reptilase 2 KU(n=60).Plasma-lyteA and Gelofusine were used on patients in the trial group.After induced with anaesthesia and intubated,those patients were then given reptilase through venous infusion.The blood samples were drown and coagulation parameters(FIB、PT、ACT、APTT)and platelets function parameters were tested before medication and 30 mins after that,and the results were compared.The bleeding volume in bottle were identically tested and kept in the record,the bleeding volume,the volume of blood transfusion were strictly counted.The losing volume in the drainage-tube was inspected in the first and the second day after the operations and Hb capacity was analyzed.Results There was no difference in coagulation parameters between two groups except FIB,but there were significant differences 30 min after being given reptilase.There was no discrepancy in parameters except bleeding volume,collective lose volume and Hb capacity.Conclusion The hemostatic effect of reptilase in anaesthesia of neurosurgery operations is very obvious.It does not affect platelets function and hemostatic effect and does not have side effect. So reptilase is a highly effective,secure and convenient drug." @default.
- W2379640269 created "2016-06-24" @default.
- W2379640269 creator A5052487639 @default.
- W2379640269 date "2007-01-01" @default.
- W2379640269 modified "2023-09-25" @default.
- W2379640269 title "Application of Reptilase in Anaesthesia of Neurosurgery" @default.
- W2379640269 hasPublicationYear "2007" @default.
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