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- W2379651490 abstract "Objective: To observe the clinical effects of Kurorinone Capsule combined Adefovir Dipivoxil Capsule in treating of patients with HBeAg positive chronic hepatitis B(CHB).Methods: To choose 104 CHB patients with HbsAg,HbeAg,HBV DNA remaining positive for more than six months,HBV DNA?Y1.0×105 copies/ml,ALT was more than 2 times upper limit of normal,TBil increased less than 3 times upper limit of normal.These patients were randomly divided into two groups,50 patients of the control group were given with Adefovir Dipivoxil Capsule,10 mg,1 time/d,oral route.On the basis of the treatment of the control group,54 patients of the treatment group were given with Kurorinone capsule 0.3,3 times/d,oral route.Symptomatic treatment measures were similar of the two groups,other anti-virus,immunity adjusting and Anti-hepatic fibrosis preparation were not used in both groups.The period of treatment was 9 months.Observing the changes of liver function(ALT,TBil),hepatitis B virus indicator(HBsAg,HBeAg,HBV DNA) and liver fibrosis indicator(HA,LN,￠?C).Results: The recovery rate of liver function and the sputum negative conversion rate of hepatitis B virus indicator of the treatment group both were greater than those of the control group.There was a statistical significance between the two groups(P0.05);the difference had no statistical significance to compare liver fibrosis indicator of two groups before treatment(P￡?0.05);the difference had a statistical significance to compare the treatment group with the control group after the treatment(P0.01),the difference had a statistical significance to compare the treatment group after the treatment with the treatment group before the treatment(P0.01).Conclusion: Kurorinone Capsule combined with Adefovir Dipivoxil Capsule in treating patients with HBeAg positive chronic hepatitis B has notable effects in the recovery of liver function,the sputum negative conversion of hepatitis B virus and the liver fibrosis indicator improvement." @default.
- W2379651490 created "2016-06-24" @default.
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- W2379651490 date "2011-01-01" @default.
- W2379651490 modified "2023-09-26" @default.
- W2379651490 title "Therapeutic effect of HBeAg positive chronic hepatitis B treated by Kurorinone Capsule combined with Adefovir Dipivoxil Capsule" @default.
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