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- W2379658268 abstract "Objective To evaluate the effects of voluven preload on hemodynamics in elderly patients undergoing total hip replacement during combined spinal epidural anesthesia.Methods 50 ASA Ⅱ or Ⅲ elderly patients of both sexes aged 69～92 yr heigth 155～182 cm and weighing 43～92kg scheduled for selective total hip replacement were randomly allocated into two groups(n=25 each),Voluven group(group V) and Lactated Ringer's solution group(group R).Voluven was infused in group V in ward at 1 hour before anesthesia and Lactated Ringer's solution was infused in group R.Combined spinal epidural anesthesia was performed at the L3～4 interspace with the patient in the contralateral position.Both groups received intrathecal 0.5% hyperbaric bupivacaine 1.5 ml at a rate of 0.1 ml/s.SBP,DBP,MAP and HR were assessed before anesthesia(T0),at 3min(T1),6 min(T2),9 min(T3),12 min(T4)and 15 min(T5) after anesthesia.Adverse effects,total times of use of ephedrine and atropine were recorded.Results Compared with group V,MAP at the time of T2 and SBP at the time of T2 and T3 were significantly lower that in group R(P0.05).The incidence of hypotension at T1-5 was significantly lower that in group V than in group R(P0.05).There were no significant differences of change in heart rate between the two groups(P0.05).Conclusion Voluven preload at 1 hour before anesthesia could maintain the stable hemodynamics in the elderly patients undergoing total hip replacement during combined spinal epidural anesthesia." @default.
- W2379658268 created "2016-06-24" @default.
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- W2379658268 date "2010-01-01" @default.
- W2379658268 modified "2023-09-23" @default.
- W2379658268 title "Effect of voluven preload on hemodynamics in elderly patients undergoing total hip replacement during combined spinal epidural anesthesia" @default.
- W2379658268 hasPublicationYear "2010" @default.
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