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- W2379722425 abstract "Objective:To observe the effects of Xin Nao Xue Mai Ning on the Expression of NF-κB mRNA,ICAM-1 mRNA and the Level of Serum Lipid.Methods:The vulnerable atherosclerotic plaque model was reproduced by operation of abdominal aorta endothelium sacculus pull injury with the high lipin forage fed cholesterol.After one week,We gave Xin Nao Xue Mai Ning to the vulnerable atherosclerotic plaque model for 12-weeks.The blood was collected for Serum Lipid test,then the animals were medico-triggered at 48h and 24h before sacrificed.The expression of NF-κB mRNA and ICAM-1 mRNA of Abdominal aorta plaques was detected by real time RT-PCR.Results:Xin Nao Xue Mai Ning could decrease the level of total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C) and at the same time markedly increase the level of high density lipoprotein cholesterol(HDL-C).Xin Nao Xue Mai Ning could decrease the expression of NF-ΚB mRNA,ICAM-1 mRNA.Conclusion:Xin Nao Xue Mai Ning could increase the stability of vulnerable atherosclerotic plaque,its mechanism of action was correlated with anti-inflammation and regulating serum lipid." @default.
- W2379722425 created "2016-06-24" @default.
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- W2379722425 date "2008-01-01" @default.
- W2379722425 modified "2023-09-28" @default.
- W2379722425 title "Effects of Xin Nao Xue Mai Ning on the Expression of NF-κB mRNA ICAM-1 mRNA and the Level of Serum Lipid" @default.
- W2379722425 hasPublicationYear "2008" @default.
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