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- W2379770402 abstract "Objective To explore the efficacy of different transplanting ways of bone marrow mesenchymal stem cells (BMSCs) in treatment of liver fibrosis. Methods The 4th generation BMSCs were cultured and induced into hepatocyte-like cells. Liver fibrosis in SD rats was inducedby carbon tetrachloride. BMSCs were transplanted by intravenous injection, intrahepatic injection and intraperitoneal injection, etc. Histopathological staining, immunohistochemistry, and biochemical analysis were used to compare the liver morphological and functional influence among different transplanting ways. Results The induced MSCs did not express hepatocyte markers, but which couldwhile expressed α-fetoprotein(AFP), and albumin(ALB). The intravenous injection way was more effective atbeneficial rescuing liver failure than other injection ways. Conclusions BMSCs transplantation was able to protect against liver fibrosis. Intravenous way was the most favorable transplanting approach." @default.
- W2379770402 created "2016-06-24" @default.
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- W2379770402 date "2013-01-01" @default.
- W2379770402 modified "2023-10-02" @default.
- W2379770402 title "Efficacy study of different transplanting ways of bone marrow mesenchymal stem cells in treatment of liver fibrosis" @default.
- W2379770402 hasPublicationYear "2013" @default.
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