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- W2379787321 abstract "Objective:To study the effects of nimesulide on proliferation and apoptosis of human gastric carcinoma cells SGC-7901 in vitro,and provide an experimental basis for clinical application.Methods:Proliferation of human gastric carcinoma cells SGC-7901 was assessed by MTT,and apoptosis was detected by transmission electron microscope and flow cytometry.Results:Proliferation of SGC-7901 was inhibited significantly by nimesulide(range from 12.5 to 800μmol/L) in a dosage-dependant manner ( P 0.05).Under transmission electron microscope and fluorescent microscope,some SGC-7901 cells undergo a typical apoptosis after 4 days incubation with nimesulide.There is an apoptosis peak.Conclusion:Nimesulide can suppress proliferation of SGC-7901 cells,which may be related to the mechanism of inducing cell apoptosis and preventing development of cell cycle." @default.
- W2379787321 created "2016-06-24" @default.
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- W2379787321 date "2004-01-01" @default.
- W2379787321 modified "2023-09-23" @default.
- W2379787321 title "Effects of nimesulide on proliferation and apoptosis of human gastric carcinoma cells SGC-7901" @default.
- W2379787321 hasPublicationYear "2004" @default.
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