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- W2379801285 abstract "OBJECTIVE To investigate the effect of total saponins of Panax noto ginseng(PNS) on augmenting endothelial regeneration and function after balloon endothelial denudation of rabbit iliac artery.METHODS Three doses of PNS(10,30,50 mg·kg~-1) were injected by iv once a day started from 2 days before operation.At 4th weeks,the animals were put to death.Relaxation induced by Ach was determined.The morphology changes of the endothelium were observed with scanning electron microscope.RESULTS The endothelium was denudated completely and Ach-induced relaxation was abolished after balloon endothelial denudation of rabbit iliac artery.Endothelial regeneration and the recovery of endothelium dependent relaxation were significantly in PNS 30,50 mg·kg~-1groups.In the group of PNS 10 mg·kg~-1 Ach-induced relaxation was the same as aspirin(4.67 mg·kg~-1) group(P0.05),but in PNS 50 mg·kg~-1 group Ach-induced relaxation was approached to that in normal control group.CONCLUSION PNS can promote the endothelial regeneration and the recovery of endothelium dependent relaxation." @default.
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- W2379801285 date "2006-01-01" @default.
- W2379801285 modified "2023-09-23" @default.
- W2379801285 title "Effect of total saponins of Panax noto-ginseng on repair of endothelial morphology and function after balloon endothelial denudation of iliac artery in rabbit" @default.
- W2379801285 hasPublicationYear "2006" @default.
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