Matches in SemOpenAlex for { <https://semopenalex.org/work/W2379808031> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2379808031 abstract "Objectives: To establish human multidrug-resistant cell line OVCAR/DDP of ovarian carcinoma and to investigate its biological characteristic.Methods: OVCAR/DDP cell line was established by stepwise selection in increasing concentration of cisplatin.Cell growth curve and population doubling time were measured and multidrug resistance to multi-anticancer agents was evaluated by MTT assay,Protein level of P-gp was evaluated by western blotting,and was investigated to determine the biological features of OVCAR/DDP cell line.Results:Compared to OVCAR,OVCAR/DDP cell had a prolonged doubling time.The OVCAR/DDP cell was 19.80 times more resistant to DDP than the OVCAR parent.OVCAR/DDP cell exhibited cross-resistance to adriamycin,Flucytosine,paclitaxel.Western blotting showed that protein level expression of P-gp was significantly increased in OVCAR/DDP.Conclusion: OVCAR/DDP shows typical multidrug resistance phenotypes and might serve as an ideal model for exploring the new route of reversing multidrug resistance." @default.
- W2379808031 created "2016-06-24" @default.
- W2379808031 creator A5065190578 @default.
- W2379808031 date "2012-01-01" @default.
- W2379808031 modified "2023-09-24" @default.
- W2379808031 title "Establishment and biological characteristics of human multidrug-resistant cell line OVCAR/DDP of ovarian carcinoma" @default.
- W2379808031 hasPublicationYear "2012" @default.
- W2379808031 type Work @default.
- W2379808031 sameAs 2379808031 @default.
- W2379808031 citedByCount "0" @default.
- W2379808031 crossrefType "journal-article" @default.
- W2379808031 hasAuthorship W2379808031A5065190578 @default.
- W2379808031 hasConcept C104317684 @default.
- W2379808031 hasConcept C114851261 @default.
- W2379808031 hasConcept C121608353 @default.
- W2379808031 hasConcept C126322002 @default.
- W2379808031 hasConcept C133936738 @default.
- W2379808031 hasConcept C143998085 @default.
- W2379808031 hasConcept C1491633281 @default.
- W2379808031 hasConcept C2776694085 @default.
- W2379808031 hasConcept C2777292972 @default.
- W2379808031 hasConcept C2778239845 @default.
- W2379808031 hasConcept C2780427987 @default.
- W2379808031 hasConcept C2908647359 @default.
- W2379808031 hasConcept C3019054536 @default.
- W2379808031 hasConcept C48900799 @default.
- W2379808031 hasConcept C502942594 @default.
- W2379808031 hasConcept C54355233 @default.
- W2379808031 hasConcept C62112901 @default.
- W2379808031 hasConcept C71924100 @default.
- W2379808031 hasConcept C81885089 @default.
- W2379808031 hasConcept C85265743 @default.
- W2379808031 hasConcept C86803240 @default.
- W2379808031 hasConcept C99454951 @default.
- W2379808031 hasConceptScore W2379808031C104317684 @default.
- W2379808031 hasConceptScore W2379808031C114851261 @default.
- W2379808031 hasConceptScore W2379808031C121608353 @default.
- W2379808031 hasConceptScore W2379808031C126322002 @default.
- W2379808031 hasConceptScore W2379808031C133936738 @default.
- W2379808031 hasConceptScore W2379808031C143998085 @default.
- W2379808031 hasConceptScore W2379808031C1491633281 @default.
- W2379808031 hasConceptScore W2379808031C2776694085 @default.
- W2379808031 hasConceptScore W2379808031C2777292972 @default.
- W2379808031 hasConceptScore W2379808031C2778239845 @default.
- W2379808031 hasConceptScore W2379808031C2780427987 @default.
- W2379808031 hasConceptScore W2379808031C2908647359 @default.
- W2379808031 hasConceptScore W2379808031C3019054536 @default.
- W2379808031 hasConceptScore W2379808031C48900799 @default.
- W2379808031 hasConceptScore W2379808031C502942594 @default.
- W2379808031 hasConceptScore W2379808031C54355233 @default.
- W2379808031 hasConceptScore W2379808031C62112901 @default.
- W2379808031 hasConceptScore W2379808031C71924100 @default.
- W2379808031 hasConceptScore W2379808031C81885089 @default.
- W2379808031 hasConceptScore W2379808031C85265743 @default.
- W2379808031 hasConceptScore W2379808031C86803240 @default.
- W2379808031 hasConceptScore W2379808031C99454951 @default.
- W2379808031 hasLocation W23798080311 @default.
- W2379808031 hasOpenAccess W2379808031 @default.
- W2379808031 hasPrimaryLocation W23798080311 @default.
- W2379808031 hasRelatedWork W2349483118 @default.
- W2379808031 hasRelatedWork W2350892610 @default.
- W2379808031 hasRelatedWork W2353314140 @default.
- W2379808031 hasRelatedWork W2358938461 @default.
- W2379808031 hasRelatedWork W2358944585 @default.
- W2379808031 hasRelatedWork W2363193798 @default.
- W2379808031 hasRelatedWork W2366373868 @default.
- W2379808031 hasRelatedWork W2370816314 @default.
- W2379808031 hasRelatedWork W2372308826 @default.
- W2379808031 hasRelatedWork W2374809056 @default.
- W2379808031 hasRelatedWork W2374957872 @default.
- W2379808031 hasRelatedWork W2376412896 @default.
- W2379808031 hasRelatedWork W2388258487 @default.
- W2379808031 hasRelatedWork W2388781544 @default.
- W2379808031 hasRelatedWork W2389031200 @default.
- W2379808031 hasRelatedWork W2409383851 @default.
- W2379808031 hasRelatedWork W2413624340 @default.
- W2379808031 hasRelatedWork W2416799924 @default.
- W2379808031 hasRelatedWork W3028838796 @default.
- W2379808031 hasRelatedWork W3030322945 @default.
- W2379808031 isParatext "false" @default.
- W2379808031 isRetracted "false" @default.
- W2379808031 magId "2379808031" @default.
- W2379808031 workType "article" @default.