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- W2379836209 abstract "Objective To establish the method to assay the contents of lidocaine and bupivacaine from compound-bupivacaine ointment. Methods The contents of lidocaine and bupivacaine in compound-bupivacaine ointment were determined by HPLC simultaneously. The analytical column: Kromasil DOS (250 mm×4.6 mm, 5 μm), the mobile phase: methanol-acetate buffer solution (pH 4.6)=65∶35, flow rate: 1.0 mL/min, detection wavelength: 245 nm, injection volume: 20 μL. Results The blank ointment did not disturb the determination. And lidocaine and bupivacaine showed linear relation in the range of 50～300 μg/mL. The average recovery ratio of lidocaine and bupivacaine were 100.1%(RSD=1.28%) and 99.1%(RSD=0.84%) respectively. Conclusion This HPLC method was accurate, reliable, rapid and simple for assay of lidocaine and bupivacaine from compound-bupivacaine ointment." @default.
- W2379836209 created "2016-06-24" @default.
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- W2379836209 date "2004-01-01" @default.
- W2379836209 modified "2023-09-22" @default.
- W2379836209 title "Simultaneous determination of two components from Compound-bupivacaine ointment by HPLC" @default.
- W2379836209 hasPublicationYear "2004" @default.
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